Kloof is a leafy, middle- to upper class suburb and small town, that includes a smaller area called Everton, in the greater Durban area of eThekwini in KwaZulu-Natal, South Africa.

The word Kloof means 'gorge' in Afrikaans and the area is named after the deep ravine formed by the Molweni stream (stream of high cliffs). The Kloof Gorge is part of the 4.47 square kilometre Krantzkloof Nature Reserve.

Kloof extends from the top of Field's Hill and borders Winston Park, Gillitts and Hillcrest. These suburbs are collectively known as the Upper Highway Area or the Outer West region of Durban.

The M13 highway (built in the 1940s) intersects Kloof and on 16 June this forms part of the route of the annual Comrades Marathon, an approximately 90km ultra-marathon run between Pietermaritzburg and Durban since 1924.